Microprocessor mediates transcriptional termination in long noncoding microRNA genes
نویسندگان
چکیده
منابع مشابه
Dhir, Ashish and Dhir, Somdutta and Proudfoot, Nick J. and Jopling, Catherine L. (2015) Microprocessor mediates transcriptional termination of long noncoding RNA
MicroRNA (miRNA) play a major role in the post-transcriptional regulation of gene expression. Mammalian miRNA biogenesis begins with co-transcriptional cleavage of RNA polymerase II (Pol II) transcripts by the Microprocessor complex. While most miRNA are located within introns of protein coding genes, a substantial minority of miRNA originate from long non coding (lnc) RNA where transcript proc...
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عنوان ژورنال:
دوره 22 شماره
صفحات -
تاریخ انتشار 2015